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<DIV><FONT size=2> dennis,
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<br>Please type the link above into your browser. <br><br>It's a long
journey, and you'd pull my arms out of joint before we'd been up an hour
Forty four trials compared a broad spectrum usually novel lactam with a
"routine" combination regimen Rates of appropriate antibiotic treatment
with combination therapy and monotherapy were similar when reported Their
faces fell at this, but one of them said: Why couldn't we swing ourselves
over your shoulders with a rope? Our two bodies would balance each other and
we are so thin and emaciated that we do not weigh very much Fatality was not
significantly different Failures were significantly more common with
combination therapy Among all trials we found no evidence for any potential
prevention of infection by resistant isolates with combination therapy
While considering this suggestion Rob remembered how at one time five
pirates had clung to his left leg and been carried some distance through the
air It can be debated which design appropriately examines the clinical
interpretation of synergism studies comparing same or different lactams
Synergism has been defined as a 2 log10 or greater reduction in bacterial
count with the combination versus that with each of the agents alone 86 In
studies comparing the same lactam this is directly tested but the effect of
increasing the antibiotic spectrum cannot be separated from a synergistic
effect </FONT>
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